Table 3.
Linear Regression Analysis for Clinicopathological Parameters and UP
| UP | ||||||
|---|---|---|---|---|---|---|
| Univariable | Multivariable | |||||
| β | t-value | P-value | β | t-value | P-value | |
| BMI (kg/m2) | 0.231 | 4.090 | <0.001 | −0.006 | −0.145 | 0.885 |
| Gender | −0.201 | −3.086 | 0.002 | 0.136 | 0.383 | 0.703 |
| Age (years) | −0.115 | −1.739 | 0.083 | - | - | - |
| L | −5.394 | −2.578 | 0.011 | −4.564 | −2.243 | 0.027 |
| ALB (g/L) | −0.436 | −7.285 | <0.001 | - | - | - |
| pALB (mg/dL) | −0.074 | −2.578 | 0.011 | −0.075 | 3.290 | 0.001 |
| GLB (g/L) | −0.215 | −3.298 | 0.001 | - | - | - |
| eGFR (mL/min) | −0.028 | −0.407 | 0.684 | - | - | - |
| TC (mmol/L) | 0.303 | 4.788 | <0.001 | - | - | - |
| TG (mmol/L) | 0.211 | 3.231 | 0.001 | - | - | - |
| LDL (mmol/L) | 0.313 | 4.817 | <0.001 | - | - | - |
| HDL (mmol/L) | 0.670 | 1.445 | 0.150 | −0.006 | −0.013 | 0.989 |
| FIB (g/L) | 0.236 | 3.609 | <0.001 | 0.185 | 1.241 | 0.217 |
| DDi (mg/L FEU) | 0.090 | 1.279 | 0.200 | −0.058 | −0.386 | 0.700 |
| IgG (g/L) | −0.359 | −5.635 | <0.001 | −0.353 | −5.021 | <0.001 |
| URBC | 0.160 | 2.375 | 0.018 | −0.016 | −2.279 | 0.025 |
| Anti-PLA2R (RU/mL) | 0.122 | 1.655 | 0.100 | 0.002 | 1.298 | 0.001 |
| IgA deposit | −0.156 | −2.373 | 0.018 | - | - | - |
| C3 deposit | 0.206 | 3.164 | 0.002 | 0.522 | 0.0173 | 0.003 |
| GS | −0.050 | −0.186 | 0.852 | - | - | - |
| MCP | 0.879 | 1.647 | 0.101 | - | - | - |
| TA | 0.120 | 1.871 | 0.071 | - | - | - |
| IF | 0.114 | 1.723 | 0.086 | - | - | - |
| VWT | 0.102 | 1.539 | 0.125 | - | - | - |
| GMTIV | 0.193 | 2.956 | 0.003 | - | - | - |
Notes: The variables involved in the multivariable linear regression model were statistically significant ones in the univariable linear regression (p≤0.2). Dashes indicate that the variable was not included in the multivariable linear regression model.
Abbreviations: BMI, body mass index; L, the ratio of lymphocyte count to white blood cell count; ALB, albumin; pALB, pre-albumin; GLB, globulin; eGFR, estimated glomerular filtration rate; TC, total cholesterol; TG, triglycerides; HDL, high-density lipoprotein; LDL, low-density lipoprotein; FIB, fibrinogen; DDi, D-Dimer; IgG, immunoglobulin G; UP, urine proteinuria concentration; URBC, the degree of urine red blood cell; Anti-PLA2R, Anti-phospholipase A2 receptor; IgA, immunoglobulin A; C3, complement 3; GS, glomerulosclerosis; MCP, mesangial cell proliferation; TA, tubular atrophy; IF, interstitial fibrosis; VWT, vascular wall thickness.