Fig 1. Urinary excretion of tetrahydroaldosterone (TH-Aldo) in diabetic patients and healthy controls.

Urinary excretion of the mineralocorticoid metabolite TH-Aldo in healthy controls (n = 155 men, n = 161 women) and diabetic patients (n = 21 men, n = 20 women) measured by GC-MS. The groups were matched for age and gender. Diabetic men significantly excreted more TH-Aldo then their controls, while this finding was not significant in women. TH-Aldo *p = 0.031 (men), ns = not significant (women). Kolmogorov-Smirnov test (non-parametric, unpaired). Dot blot is shown with Log (10) scale and steroid concentrations are displayed in ug/24h. White circles = control men, black circles = diabetic men, white squares = control women, black squares = diabetic women. *p<0.05, **p<0.01, ***p<0.0001, ns = not significant.