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. 2022 Jun 24;17(6):e0269920. doi: 10.1371/journal.pone.0269920

Table 3. Absolute values of the calculated enzymatic activities of the two human cohorts.

Calculated enzymatic activities mean +/- SEM, n p-value
CYP11B2 (THB/TH-Aldo) diabetic men 6.479 ± 1.299, n = 21 0.027
CYP11B2 (THB/TH-Aldo) control men 8.882 ± 0.5929, n = 155
CYP11B2 (THB/TH-Aldo) diabetic women 6.241 ± 1.042, n = 20 0.834
CYP11B2 (THB/TH-Aldo) control women 6.411 ± 0.3256, n = 161
CYP11B2 (18-OH-THA/TH-Aldo) diabetic men 4.808 ± 1.545, n = 21 0.541
CYP11B2 (18-OH-THA/TH-Aldo) control men 3.867 ± 0.4918, n = 155
CYP11B2 (18-OH-THA/TH-Aldo) diabetic women 5.607 ± 1.395, n = 20 0.144
CYP11B2 (18-OH-THA/TH-Aldo) control women 3.317 ± 0.3976, n = 161
CYP11B1 (THS/cortisol) diabetic men 1.176 ± 0.298, n = 21 <0.0001
CYP11B1 (THS/cortisol) control men 0.4697 ± 0.02239, n = 155
CYP11B1 (THS/cortisol) diabetic women 0.6595 ± 0.08961, n = 20 0.0595
CYP11B1 (THS/cortisol) control women 0.4829 ± 0.02434, n = 161
HSD11B2 (F/E) diabetic men 0.7214 ± 0.08597, n = 21 0.0004
HSD11B2 (F/E) control men 0.9214 ± 0.02052, n = 155
HSD11B2 (F/E) diabetic women 0.7795 ± 0.1299, n = 20 0.0002
HSD11B2 (F/E) control women 0.9215 ± 0.02232, n = 161
Whole HSD11B (THF+5α-THF)/THE diabetic men 1.119 ± 0.0709, n = 21 0.1504
Whole HSD11B (THF+5α-THF)/THE control men 1.663± 0.1720, n = 151
Whole HSD11B (THF+5α-THF)/THE diabetic women 1.141 ± 0.1458, n = 20 0.1396
Whole HSD11B (THF+5α-THF)/THE control women 2.071 ± 0.4288, n = 158