. 2022 Jun 8;31(11-12):322–333. doi: 10.1089/scd.2022.0004

Table 1.

Effects of IL-4, IL-13, and IL-10 on Expression of Their Receptors in CSF-1-Primed Cells

Target Treatment	IL-4R	P value^a	IL-13R	P value	IL-10R	P Value
Percent of positive cells^b
None (Ex vivo)^c	7.10 ± 0.80	N/A	13.50 ± 0.40	N/A	6.20 ± 0.20	N/A
CSF-1	31.55 ± 3.00	N/A	60.15 ± 0.30	N/A	38.80 ± 7.63	N/A
IL-4	N/D	N/A	N/D	N/A	N/D	N/A
CSF-1 + IL-4	72.05 ± 1.55	<0.05	59.85 ± 1.34	0.4531	98.55 ± 0.21	<0.05
IL-13	N/D	N/A	N/D	N/A	N/D	N/A
CSF-1 + IL-13	86.63 ± 3.98	<0.05	75.17 ± 4.06	<0.05	89.15 ± 0.32	<0.05
IL-10	N/D	N/A	N/D	N/A	N/D	N/A
CSF-1 + IL-10	95.87 ± 2.67	<0.05	94.00 ± 2.53	<0.05	90.95 ± 1.85	<0.05
Mean fluorescent intensity ( × 10³)^b
None (Ex vivo)	19.30 ± 0.20	N/A	79.3 0 ± 3.50	N/A	35.99 ± 11.50	N/A
CSF-1	28.80 ± 1.94	N/A	56.71 ± 1.85	N/A	42.90 ± 0.88	N/A
IL-4	N/D	N/A	N/D	N/A	N/D	N/A
CSF-1 + IL-4	69.51 ± 16.68	<0.05	73.19 ± 2.66	<0.05	44.82 ± 2.76	<0.05
IL-13	N/D	N/A	N/D	N/A	N/D	N/A
CSF-1 + IL-13	105.41 ± 12.04	<0.05	87.46 ± 2.58	0.0980	63.81 ± 3.77	<0.05
IL-10	N/D	N/A	N/D	N/A	N/D	N/A
CSF-1 + IL-10	125.60 ± 11.25	<0.05	115.57 ± 9.95	<0.05	52.33 ± 1.90	<0.05

^{^a}

P values indicate significant differences compared with CSF-1 alone.

^{^b}

Percent of positive cells and mean fluorescent intensity values are presented as mean ± SD of three to five independent experiments performed in duplicate on day 6.

^{^c}

Ex vivo analysis was performed on the day of cell isolation.

N/A, not applicable; N/D, not done; analyses were not performed due to low cell survival.