Table 2.
Baseline clinical and pathological characteristics of patients by large-volume LNM status.
| Training cohort | p value | Validation cohort | p value | |||
|---|---|---|---|---|---|---|
| Positive (n = 19) | Negative (n = 164) | Positive (n = 11) | Negative (n = 112) | |||
| Clinical characteristics | ||||||
| Age (years) | ||||||
| <40 | 12 (63.2) | 53 (32.3) | 0.016 | 7 (63.6) | 36 (32.1) | 0.049 |
| ≥40 | 7 (36.8) | 111 (67.7) | 4 (36.4) | 76 (67.9) | ||
| Gender | ||||||
| Male | 9 (47.4) | 32 (19.5) | 0.014 | 5 (45.5) | 19 (17.0) | 0.038 |
| Female | 10 (52.6) | 132 (80.5) | 6 (54.5) | 93 (83.0) | ||
| Capsule invasion | ||||||
| Positive | 14 (73.7) | 98 (59.8) | 0.352 | 6 (54.5) | 78 (69.6) | 0.492 |
| Negative | 5 (26.3) | 66 (40.2) | 5 (45.5) | 34 (30.4) | ||
| Tumor size (mm) | 12 (7–14) | 12 (7–14) | 0.215 | 12 (12–15) | 12 (9–14) | 0.357 |
| ACR TI-RADS score | 9 (8–10) | 9 (7–10) | 0.351 | 9 (7–9) | 9 (7–10) | 0.699 |
| ACR TI-RADS grade | ||||||
| TR 1–4 | 0 (0) | 30 (18.3) | 0.047 | 1 (9.1) | 22 (19.6) | 0.688 |
| TR 5 | 19 (100) | 134 (81.7) | 10 (90.9) | 90 (80.4) | ||
| Pathological characteristics | ||||||
| Pathologic T stage | ||||||
| pT1 | 15 (78.9) | 142 (86.6) | 0.528 | 9 (81.8) | 90 (80.4) | 1.000 |
| pT2 | 3 (15.8) | 14 (8.5) | 1 (9.1) | 10 (8.9) | ||
| pT3 | 1 (5.3) | 6 (3.7) | 1 (9.1) | 11 (9.8) | ||
| pT4 | 0 (0) | 2 (1.2) | 0 (0) | 1 (0.9) | ||
| Pathologic N stage | ||||||
| pN0 | 0 (0) | 118 (72.0) | <0.001 | 0 (0) | 83 (74.1) | <0.001 |
| pN1a | 19 (100) | 41 (25.0) | 9 (91.8) | 29 (25.9) | ||
| pN1b | 0 (0) | 5 (3.0) | 2 (18.2) | 0 (0) | ||
| Multifocality | ||||||
| Positive | 10 (52.6) | 81 (49.4) | 0.980 | 6 (54.5) | 49 (43.8) | 0.712 |
| Negative | 9 (47.4) | 83 (50.6) | 5 (45.5) | 63 (56.2) | ||
| Hashimoto's thyroiditis | ||||||
| Positive | 7 (36.8) | 60 (36.6) | 1.000 | 6 (54.5) | 35 (31.2) | 0.219 |
| Negative | 12 (63.2) | 104 (63.4) | 5 (45.5) | 77 (68.8) | ||
ACR TI-RADS, American College of Radiology Thyroid Imaging, Reporting and Data System.