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. 2022 Jun 17;2022:8278744. doi: 10.1155/2022/8278744

Table 2.

Subgroup analysis about trial duration, standard curcumin dose, and other therapy.

Subgroup and variable Trials number Mean difference (mg/dL) 95% CI P P-h
TG
 Duration
  >8w 5 −17.473 (−37.464, 2.517) 0.087 0.008
  ≤8w 4 −21.614 (−56.314, 13.086) 0.222 ≤0.001
 Standard curcumin dose
  >100 mg/day 6 −28.944 (−49.620, −8.268) 0.006 ≤0.001
  ≤100 mg/day 3 −18.974(−36.473, −1.474) 0.173 0.698
 Other therapy
  Y 5 −39.449 (−65.370, −13.527) 0.003 0.004
  N 4 2.275 (−6.819, 11.369) 0.624 0.382

LDL-c
 Duration
  >8w 5 −2.873 (−15.134, 9.388) 0.646 0.018
  ≤8w 4 −5.990 (−13.292, 1.312) 0.108 0.295
 Standard curcumin dose
  >100 mg/day 6 −4.118 (−14.116, 5.880) 0.419 0.26
  ≤100 mg/day 3 −3.729 (−14.089, 6.630) 0.480 0.212
 Other therapy
  Y 5 −9.260 (−16.271, −2.248) 0.010 0.356
  N 4 1.529 (−9.945, 13.003) 0.794 0.38

HbA1c (%)
 Duration
  >8w 5 −0.749 (−1.059, −0.439) ≤0.001 0.183
  ≤8w 3 −0.170 (-0.432, 0.092) 0.205 0.304
 Standard curcumin dose
  >100 mg/day 6 −0.495 (−0.777, −0.213) 0.001 0.032
  ≤100 mg/day 2 −0.693 (−1.711, 0.325) 0.182 0.005
 Other therapy
  Y 4 −0.483 (−0.735, −0.231) ≤0.001 0.337
  N 4 −0.551 (−0.983, −0.120) 0.012 0.001

FBG
 Duration
  >8w 5 −10.893 (−21.149, −0.636) 0.037 0.054
  ≤8w 4 −7.620 (−14.845, −0.395) 0.039 0.234
 Standard curcumin dose
  >100 mg/day 6 −9.798 (−16.375, −3.221) 0.004 0.089
  ≤100 mg/day 3 −2.000 (−20.593, 16.592) 0.833 0.134
 Other therapy
  Y 5 −15.185 (−24.819, −5.550) 0.002 0.251
  N 4 −5.757 (−10.871, −0.643) 0.027 0.262