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. 2022 Apr 20;47(4):523–535. doi: 10.1007/s13318-022-00767-8

Table 3.

Covariate analysis

Covariate ΔOFV Covariate effect Included after forward inclusion Included after backward elimination
Haematocrit − 6.752 − 0.906 Yes Yes
Albumin − 0.001 − 0.0143 No No
Weight − 6.362 0.514 Yes No
LBW − 8.395 0.787 Yes Yes
IBW − 8.405 1.07 Yes No
BSA − 7.998 0.955 Yes No
Sex − 0.537 0.916 No No
Age − 0.792 0.126 No No
ABCB1 1199G>A
 AA − 0.474 0.702 No No
 GA − 0.107 1.06 No No
 GG − 0.537 0.916 No No
ABCB1 3435C>T
 CC − 3.431 0.817 No No
 CT − 2.515 1.15 No No
 TT − 0.011 1.01 No No

OFV objective function value, LBW lean body weight, IBW ideal body weight, BSA body surface area