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. 2022 Jun 24;12:10726. doi: 10.1038/s41598-022-14291-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Neurofilament density volume in the olfactory bulb negatively correlates with serum neurofilament light chain (NfL) levels in contrast to the other regions. This suggests that changes in NfL serum levels in experimental cerebral malaria (ECM) are mainly driven by the location of brain injury and reflect less brain injuries as a sum. (n_{healthy control} = 3 per region, n_{reversible edema} = 3 per region, n_{irreversible edema} = 3 per region).