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. Author manuscript; available in PMC: 2023 Jul 1.
Published in final edited form as: Eur J Nucl Med Mol Imaging. 2022 Jan 31;49(8):2844–2868. doi: 10.1007/s00259-022-05706-y

Table 1.

Summary of representative clinical studies evaluating FAPI PET/CT

Authors Year Radiopharmaceutical Population Number
of patients
Method Ref
Lindner et al 2018 68 Ga-FAPI-04 Breast cancer 2 Prospective [35]
Giesel et al 2019 68 Ga-FAPI-02/04; 18F-FDG Mixed population of different cancers 50 Prospective [27]
Hathi et al 2019 68 Ga-FAPI-04 Mixed population of different cancers 54 Prospective [33]
Röhrich et al 2019 68 Ga-FAPI-02/04 Glioma 18 Prospective [46]
Chen et al 2020 68 Ga-FAPI-04; 1SF-FDG Mixed population of different cancers 75 Prospective [154]
Chen et al 2020 68 Ga-FAPI-04; 1SF-FDG Mixed patients with inconclusive 18F-FDG findings 68 Prospective [155]
Syed et al 2020 68 Ga-FAPI-04 Head and neck cancers 14 Prospective [134]
Giesel et al 2020 18F-FAPI-74;68 Ga-FAPI-74 Lung cancers 10 Prospective [42]
Shi et al 2020 68 Ga-FAPI-04 Hepatobiliary cancers 25 Prospective [66]
Koerber et al 2020 68 Ga-FAPI-04/46 Colorectal and anal cancers 16 Prospective [60]
Luo et al 2020 68 Ga-FAPI-04; 1SF-FDG IgG4-RD 26 Prospective [97]
Lindner et al 2020 99mTc-FAPI-34 Ovarian and pancreatic cancers 2 Prospective [144]
Zhang et al 2021 68 Ga-FAPI-04 Mixed patients with different diseases 103 Retrospective [72]
Zhao et al 2021 68 Ga-DOTA-2P(FAPI)2 Healthy volunteers and different cancer patients 6 Prospective [141]
Mona et al 2021 68 Ga-FAPI-46 Mixed patients with different diseases 141 Prospective [156]
Gundogan et al 2021 68 Ga-FAPI-04 Gastric adenocarcinoma 21 Prospective [157]
Pang et al 2021 68 Ga-FAPI-04 Pancreatic cancers 36 Retrospective [71]
Ballal et al 2021 68 Ga-DOTA.SA.FAPI Radioiodine-refractory differentiated thyroid cancer 15 Prospective [143]
Lan et al 2021 68 Ga-FAPI-04 Mixed patients with different diseases 123 Prospective [158]
Kuten et al 2021 68 Ga-FAPI-04 Gastric adenocarcinoma 13 Prospective [57]
Qin et al 2021 68 Ga-FAPI-04 Nasopharyngeal carcinoma 15 Prospective [39]
Qin et al 2021 68 Ga-FAPI-04 Gastric carcinomas 20 Prospective [59]