Table 1.

Two-stage framework of Phase 1 trial enrollment (Garrett et al., 2020).

Activity	Description
Stage 1: Setting the Stage	Involves deliberations about whether oncologists support early phase participation and whether the patient is interested.
Part 1: Oncologist Support	Oncologists determine whether a clinical trial is appropriate for the patient and whether there is one available.
Part 2: Patient Interest	Patients are open to or express interest in clinical trials.
Stage 2: Securing a Seat	Occurs after stage 1 or concurrently. Involves identifying an open trial, affirming eligibility, and obtaining informed consent.