Table 3.
Lymphoma Italian Foundation Simplified Geriatric Assessment and Elderly Prognostic Index.
| Simplified geriatric assessment | ||||
|---|---|---|---|---|
| Criteria | Fit | Unfit(<80) | Unfit (≥80) | Frail |
| ADL | ≥5 | <5 | 6 | <6 |
| IADL | ≥6 | <6 | 8 | <8 |
| CIRS-G | No comorbidities with score = 3–4, ≤8 with score = 2 | ≥1 with score = 3–4, >8 with score = 2 | No comorbidities with score = 3–4, <5 with score = 2 | ≥1 with score = 3–4, ≥5 with score = 2 |
| Age - years | <80 | <80 | ≥80 | ≥80 |
| Elderly prognostic index | ||||
|---|---|---|---|---|
| Criteria | Score | HR (95% CI) | P-value | |
| sGA | Fit | 0 | 1.00 | |
| Unfit | 3 | 1.93 (1.49 to 2.50) | <0.001 | |
| Frail | 4 | 2.74 (2.07 to 3.62) | <0.001 | |
| IPI | IPI 1 | 0 | 1.00 | |
| IPI 2 | 1 | 1.55 (0.99 to 2.44) | 0.055 | |
| IPI 3–5 | 3 | 2.90 (1.93 to 4.35) | <0.001 | |
| Hemoglobin <12 g/dL | 1 | 1.28 (1.02 to 1.60) | 0.033 | |
| Risk Groups (score) | 3-year OS (95% CI) | HR (95% CI) | P-value |
|---|---|---|---|
| Low (0–1) | 87% (81–91) | 1.00 | |
| Intermediate (3–5) | 69% (63–73) | 2.57 (1.72 to 3.84) | <0.001 |
| High (6–8) | 42% (36–49) | 6.21 (4.17 to 9.25) | <0.001 |
ADL: Activities of Daily Living, IADL: Instrumental Activities of Daily Living; CIRS-G – Comorbidities Illness Rating Scale – Geriatric; sGA: simplified geriatric assessment; IPI: international prognostic index.