Table 1: Pdpn modulates Src kinase mediated phosphorylation events.
Protein symbol, name, and phosphorylation sites are shown along with difference of induction (Δ Induction) shown as a ratio of phosphorylation events in PdpnWTstSrc cells at permissive (34°C)/nonpermissive (39°C) temperatures over phosphorylation events seen in PdpnKOtsSrc cells at permissive (34°C)/nonpermissive (39°C) temperatures (mean, n=2). Some phosphorylation events can be attributed to more than one protein as indicated.
| Symbol | Name | Annotated Sequence | Δ Induction |
|---|---|---|---|
| Rbl2 | RB transcriptional corepressor like 2 | 624-YSS*PTVSTTR-633 | 2.2 |
| Parp12 | poly (ADP-ribose) polymerase family member 12 | 457-NLVYGT*IR-464 | 2.1 |
| Rftn1 | Raftlin | 481-QGS*AAVQNGPAGHNR-495 | 2.1 |
| Rab11fip3 | RAB11 family interacting protein 3 | 937-SSS*LGLQEYNSR-948 | 1.9 |
| Chaf1a | chromatin assembly factor 1 subunit A | 290-GGRSSPST*PACR-301 | 1.8 |
| Cirbp | cold inducible RNA binding protein | 146-SQGGS*YGYR-154 | 1.8 |
| Nelfa | negative elongation factor complex member A | 225-SPTTPSVFS*PSGNR-238 | 1.7 |
| Rbm3 | RNA binding motif protein 3 | 115-YDS*RPGGYGYGYGR-128 | 1.7 |
| Pcnt | Pericentrin | 2680-QDGTDLQSS*LR-2690 | 1.6 |
| Gas2l1 | growth arrest-specific 2 like 1 | 371-SDDSATGS*RR-380 | 1.6 |
| Micall2 | MICAL-like 2 | 638-S*PSIS*PR-644 | 1.6 |
| Matr3 | matrin 3 | 252-FDSEY*ER-258 | 1.6 |
| Myh11 Myh9 Myh14 |
myosin heavy polypeptide 11 myosin heavy polypeptide 9 myosin heavy polypeptide 14 |
556-ATDKS*FVEK-564 537-ATDKS*FVEK-545 567-ATDKS*FVEK-575 |
1.6 |
| Hectd1 | HECT domain E3 ubiquitin protein ligase 1 | 1563-TNATNNMNLS*R-1573 | 1.6 |
| Champ1 | chromosome alignment maintaining phosphoprotein 1 | 582-CDSLAQEGLLAT*PK-595 | 1.6 |
| Cd44 | CD44 antigen | 304-KLVINGGNGT*VEDR-317 | 1.6 |
| Lin54 | lin-54 DREAM MuvB core complex component | 307-IAIS*PLKS*PNK-317 | 1.6 |
| Epb41 | erythrocyte membrane protein band 4.1 | 712-RLS*THS*PFR-720 | 1.6 |
| Kdm3b | KDM3B lysine (K)-specific demethylase 3B | 308-GEVDSNGS*DGGEASR-322 | 1.6 |
| Flrt3 | fibronectin leucine rich transmembrane protein 3 | 582-KDNS*ILEIR-590 | 1.6 |
| Scarf2 | scavenger receptor class F member 2 | 467-RELT*LGR-473 | 1.6 |
| Ogdh Ogdhl |
oxoglutarate dehydrogenase oxoglutarate dehydrogenase-like |
457-SS*PYPTDVAR-466 444-SS*PYPTDVAR-453 |
1.6 |
| E2f8 | E2F transcription factor 8 | 142-AESSQNS*PPVPNK-154 | 1.5 |
| Adnp | activity-dependent neuroprotective protein | 95-NVHS*EDFENR-104 | 1.5 |
| Fads2 | fatty acid desaturase 2 | 4-GGNQGEGS*TER-14 | 1.5 |
| Mybbp1a | MYB binding protein 1a | 1215-DQPPS*T*GKK-1223 | 1.5 |
| Dtl | denticleless E3 ubiquitin protein ligase | 671-AENSSPRS*PSSQTPSSR-687 | 1.5 |