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. Author manuscript; available in PMC: 2023 Jun 21.
Published in final edited form as: Chemistry. 2022 May 12;28(35):e202200994. doi: 10.1002/chem.202200994

Figure 1.

Figure 1.

RIP-mediated depurination of A15 in the α-sarcin/ricin loop RNA substrate yields an abasic site. R1, R1a, R1b, R2a are the native, tzG16, thG16, and tzG14 modified hairpin substrates, respectively. R = d-ribose