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. Author manuscript; available in PMC: 2023 Jun 16.
Published in final edited form as: Mol Cell. 2022 May 3;82(12):2267–2297. doi: 10.1016/j.molcel.2022.04.014

Figure 1.

Figure 1.

Factors that Suppress and Resolve R-loops. Factors that prevent the formation of R-loops or play a role in their resolution as referenced throughout the text. The black line is parental DNA, blue lines are daughter DNA, and RNA is depicted by red lines. The stacked structure on the ssDNA strand of the R-loop represents a G-quadruplex.