. Author manuscript; available in PMC: 2023 Jul 1.

Published in final edited form as: J Am Acad Dermatol. 2022 Mar 18;87(1):80–86. doi: 10.1016/j.jaad.2022.02.067

Table 2.

Facial AK clearance rates after PDT in relation to Vitamin D status prior to treatment, and with or without oral VD3 pretreatment

	Group 1 (PDT only)	Group 2 (VD3 + PDT)
Vitamin D deficient (< 31 mg/dL)
No. of patients (n)	7	8
25OH-D3 values (mg/dL), range	14.9 to 29.3	14.2 to 28.7
AK clearance (%, mean ± SD)	40.9 ± 48	71.0 ± 6.0
Vitamin D sufficient (> 31 mg/dL)
No. of patients (n)	22	21
25OH-D3 values (mg/dL), range	32.0 to 83.3	31.0 to 100
AK clearance (%, mean ± SD)	62.6 ± 14.2	73.1 ± 15.9
Are the Vitamin D deficient and replete groups statistically different? ^*	Yes, p<0.014	No, p = 0.71
All patients	29	29
AK clearance (%, mean ± SD)	54.4 ± 22.8	72.5 ± 13.6
Statistical comparison of AK clearance
between Groups 1 and 2 ^**	-----	p < 0.002

FOOTNOTES:

^(*)

P-value, Student t-test

^(**)

P-value, multivariate regression analysis which includes the % decrease in number of lesions on the face while adjusting for age, sex, pre-treatment lesion counts, and length of time to follow-up.