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A: Structures of TRPV1, TRPA1 and TRPM8 are illustrated, together with the genetic tree of TRP channel superfamily.
B: Top view of transmembrane domain of TRPV1, illustrating the domain swapped tetrameric architecture of TRP channel in general.
C – E: Details of domain architectures illustrated for a single subunit for TRPV1 (C), TRPA1 (D) and TRPM8 (E).
