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. Author manuscript; available in PMC: 2022 Aug 15.
Published in final edited form as: Neuroimage. 2022 May 10;257:119296. doi: 10.1016/j.neuroimage.2022.119296

Fig. 7. The DRTMLE deconfounded group difference revealed more extensive differences than the naïve approach.

Fig. 7.

Z-statistics for ASD versus TD using a) the naïve test and b) using DRTMLE. Connections are thresholded using a false discovery rate (FDR) of 0.20. Blue lines indicate ASD > TD (4 in naïve, 13 in DRTMLE). Red lines indicate ASD < TD (4 in naïve, 12 in DRTMLE). Brain regions contributing to each independent component are illustrated and components are grouped by functional assignment. Navy nodes: control. Blue violet: default mode. Purple: salience/ventral attention. Magenta: pontomedullary/cerebellar. Coral: somatomotor. Orange: visual. Yellow: dorsal attention. FDR=0.05 is plotted in Web Supplement Fig. S3. See Web Supplement Fig. S4 for a visualization of the naïve and deconfounded means and individual-level partial correlations. These plots were generated using the circlize package in R (Gu et al., 2014) and the tutorial provided by Mowinckel (2018).