Figure 3.
Phenotypic comparison of the Ins2Akita mutation in males of three inbred strains show comparable levels in hyperglycemia in Akita/+ males in all three genetic backgrounds (A). Following necropsy at 6 months of age, development of diabetic nephropathy was only limited to the DBA/2J strain as measured by the increased albumin/creatinine ratio (data from the Diabetes Complications Consortium)