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GIPR agonism does attenuate CTA induced by broad aversive agents. Saccharin preference ratio in lean C57/Bl6 mice dosed once with LiCl (intraperitoneally) and growth differentiation factor 15 (GDF15) (subcutaneously) alone (A and C) and in combination (B and D) with a GIPRA (subcutaneously) (n = 6 per group). Values are means ± SEM. *P < 0.05 vs. vehicle (Veh). Statistical analyses performed included a one-way ANOVA, followed by Dunnett multiple comparisons test where appropriate.
