Figure 7. The effect of the connexin expressed in irradiated cells on genomic instability in distant progeny of bystander cells.

Micronucleus formation in the progeny of bystander AG1522 cells that were co-cultured with either AG1522 cells, HeLa cells devoid of functional connexins, or HeLa cells expressing either Cx26, Cx32 or Cx43 within minutes following exposure to mean absorbed doses of 0 or 50 cGy of 3.7 MeV α particles. Micronuclei formation was assayed in progeny cells that underwent 24 population doublings.