Figure 1.
TMEM59 mRNA expression is decreased in ASD patients. A, Quantification of TMEM59 mRNA levels in lymphoblastoid cells of controls and ASD patients with a 15q11–q13 duplication [dup(15q)] or a fragile X mutation (FMR1-FM). n = 15 for control, n = 7 for dup(15q), and n = 8 for FMR1-FM, one-way ANOVA followed by Tukey's post hoc test. Data from Gene Expression Omnibus (GEO) profile database, ID: 41720291. B, Quantification of TMEM59 mRNA levels in peripheral blood lymphocytes of autistic children and controls. n = 69 for control and n = 77 for autism, unpaired t test. Data from GEO profile database, ID: 92270468. Data represent mean ± SEM; *p < 0.05, **p < 0.01.
