Table 5.

Effect of pcDNA-TLR4 on the TLR4/MyD88/NF-κB pathway.

Group	TLR4	MyD88	NF-κB
pcDNA-CON	0.91 ± 0.12	1.09 ± 0.11	1.12 ± 0.08
pcDNA-TLR4	1.25 ± 0.09+	0.71 ± 0.08+	0.74 ± 0.13+
pcDNA − CON + miR − 146a	0.69 ± 0.11+	1.21 ± 0.14+	1.18 ± 0.12+
pcDNA − TLR4 + miR − 146a	1.11 ± 0.14∗	0.93 ± 0.09∗	0.87 ± 0.11∗
F	35.114	32.393	86.591
P	<0.001	<0.001	<0.001

Note. ⁺ and ^∗ are comparisons with the pcDNA-CON and pcDNA − CON + miR − 146a groups, respectively; P < 0.05; n = 3.