Table 2.
Odds ratios of ICH outcomes for LDL-C and SBP levels measured at baseline.
| Variables | Case (%) | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | ||||
| LDL-C | Hematoma expansion | |||||
| <70 mg/dL | 1102 (9.26) | 1.19 (1.11, 1.28) | 1.19 (1.11, 1.28) | 1.17 (1.09, 1.26) | 1.22 (1.10, 1.35) | |
| 70-100 mg/dL | 1977 (7.92) | 1.01 (0.95, 1.07) | 1.00 (0.95, 1.07) | 1.02 (0.96, 1.08) | 1.02 (0.94, 1.11) | |
| ≥100 mg/dL | 3037 (7.87) | Ref. | Ref. | Ref. | Ref. | |
| In-hospital mortality | ||||||
| <70 mg/dL | 296 (2.49) | 1.24 (1.08, 1.42) | 1.16 (1.01, 1.33) | 1.16 (1.01, 1.33) | 0.91 (0.76, 1.08) | |
| 70-100 mg/dL | 500 (2.00) | 0.99 (0.88, 1.11) | 0.95 (0.85, 1.06) | 0.96 (0.86, 1.08) | 0.87 (0.75, 1.00) | |
| ≥100 mg/dL | 780 (2.02) | Ref. | Ref. | Ref. | Ref. | |
| SBP | Hematoma expansion | |||||
| <140 mmHg | 1055 (8.33) | 0.95 (0.87, 1.02) | 0.95 (0.88, 1.02) | 0.90 (0.83, 0.98) | 0.82 (0.73, 0.93) | |
| 140-180 mmHg | 3074 (7.66) | 0.86 (0.81, 0.91) | 0.86 (0.81, 0.91) | 0.83 (0.78, 0.88) | 0.78 (0.72, 0.85) | |
| ≥180 mmHg | 1987 (8.78) | Ref. | Ref. | Ref. | Ref. | |
| In-hospital mortality | ||||||
| <140 mmHg | 213 (1.68) | 0.51 (0.44, 0.60) | 0.52 (0.45, 0.61) | 0.51 (0.43, 0.59) | 0.74 (0.60, 0.90) | |
| 140-180 mmHg | 633 (1.58) | 0.48 (0.43, 0.54) | 0.47 (0.43, 0.53) | 0.47 (0.42, 0.52) | 0.67 (0.58, 0.76) | |
| ≥180 mmHg | 730 (3.22) | Ref. | Ref. | Ref. | Ref. | |
Data are OR (95% CI) unless otherwise stated. Model 1 adjusted for age and sex. Model 2 adjusted for variables in model 1 plus body mass index (<25.0 or ≥25.0 kg/m2), systolic blood pressure, diastolic blood pressure, smoking status, drinking status, hypertension, diabetes mellitus, previous ICH, medication history (including prior use of antiplatelet, anticoagulant, antihypertensive agent, and stains), and creatinine. Model 3 adjusted for variables in model 2 plus GCS score on admission as a sensitivity analysis.