Table 1.
Baseline characteristics of the entire SAH cohort and comparison between patients developing increased intracranial pressure or not
| All (n = 335) | No ICP increase (n = 253) | ICP increase (n = 82) | p value | |
|---|---|---|---|---|
| Demographics | ||||
| Age—years; mean ± SD | 55.1 ± 13.1 | 56.0 ± 13.4 (23–90) | 52.1 ± 10.5 (19–72) | 0.053 |
| Sex—female/male; no. (%) | 233 (69.6)/102 (30.4) | 173 (68.4) / 80 (31.6) | 60 (73.2)/22 (26.8) | 0.413 |
| Comorbidity | ||||
| Hypertension; no. (%) | 144 (43.0) | 114 (45.2) | 30 (36.6) | 0.169 |
| Smoking; no. (%) | 108 (32.2) | 83 (32.9) | 25 (30.5) | 0.681 |
| Diabetes; no. (%) | 14 (4.2) | 13 (5.2) | 1 (1.2) | 0.122 |
| BMI; median (IQR) | 25.0 (6) | 25 (5) | 25 (6) | 0.607 |
| Aneurysm location; no. (%) | 0.003 | |||
| Acomm | 100 (30.0) | 83 (32.8) | 17 (20.7) | |
| MCA | 96 (28.7) | 58 (22.9) | 38 (46.3) | |
| ICA | 43 (12.8) | 28 (11.1) | 15 (18.3) | |
| Others | 96 (28.7) | 84 (33.2) | 12 (14.6) | |
| Ant. circulation | 264 (78.8) | 191 (75.5) | 73 (89.0) | 0.009 |
| Post. circulation | 71 (21.1) | 62 (24.5) | 9 (11.0) | |
|
Aneurysm size Max. diameter (mm)—mean ± SD |
6.0 ± 4.0 | 6.0 ± 4.0 | 7.0 ± 5.0 | 0.017 |
| Hemorrhage severity | ||||
| Hunt and Hess grade; no. (%) | < 0.001 | |||
| Grade 1 | 65 (19.4) | 61 (24.1) | 4 (4.9) | |
| Grade 2 | 80 (23.9) | 68 (26.9) | 12 (14.6) | |
| Grade 3 | 96 (28.7) | 75 (29.6) | 21 (25.6) | |
| Grade 4 | 53 (15.8) | 28 (11.1) | 25 (30.5) | |
| Grade 5 | 41 (12.2) | 21 (8.3) | 20 (24.4) | |
| Modified Fisher scale; no. (%) | < 0.001 | |||
| Grade 1 | 82 (24.5) | 76 (30.0) | 6 (7.3) | |
| Grade 2 | 46 (13.7) | 39 (15.4) | 7 (8.5) | |
| Grade 3 | 98 (29.3) | 72 (28.5) | 26 (31.7) | |
| Grade 4 | 109 (32.5) | 66 (26.1) | 43 (52.4) | |
| Acute hydrocephalus; no. (%) | 218 (65.1) | 154 (61.1) | 64 (78.0) | 0.005 |
| Aneurysm occlusion; no. (%) | ||||
| Clipping/endovascular | 152 (45.4)/183 (54.6) | 106 (41.9)/147 (58.1) | 46 (56.1)/36 (43.9) | 0.025 |
| Invasive neuromonitoring (ptiO2/CMD); no. (%) | 99 (29.6) | 59 (23.3) | 40 (48.8) | < 0.001 |
Acomm anterior communication artery; BMI body mass index; DHC decompressive hemicraniectomy; ICA internal carotid artery; MCA middle cerebral artery; SAH subarachnoid hemorrhage