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. 2022 Jan 11;13(10):760–777. doi: 10.1007/s13238-021-00895-y

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The structures and interaction details of two copies of Nup214 complexes in each CR subunit. (A) Domain assignment of modeled parts of Nup214, Nup88 and Nup62. (B) Location of 16 copies of the Nup214 complex in CR. The Nup214 complex in each subunit is colored differently. (C) Location of 2 copies of the Nup214 complex in the CR subunit. The left Nup214 complex is colored in chartreuse, and the right Nup214 complex is colored in light pink. (D) Model of the left and right Nup214 complex attached to two CR subunits. (E) Domain display of left and right Nup214 complexes. (F) Interaction sites of left and right Nup214 complexes