FIGURE 9.

Evaluation of selected peptides against pneumococcal oxidative stress resistance. (a) Survival of pneumococcal strains after treatment with 1 mM paraquat. (b) The addition of 1 μM SHP144 reconstitutes Δshp144 oxidative stress resistance but not SHP S14A. (c) Inhibition of pneumococcal oxidative stress resistance using 10 μM SHP P21A. This inhibition was not seen with SHP S14A. The survival percentages were calculated for each strain grown in THY in the presence or absence of the selected peptide. Comparisons were made relative to wild type or Δshp144. Data represent the average of at least three independent experiments, each with triplicates. *p < .05, **p < .01, “ns” p > .05.