Table 1.

CD138 and Kappa immunostaining patterns in various tissues

Organ/tissue	CD138	Kappa
Small intestine
Plasmacytes	Peyer’s patches (++) Lamina propria of villi (++)	Peyer’s patches (++) Lamina propria of villi (++)
Enterocytes	Enterocytes (crypts > surface) (Neg to ++)	(Neg)
Liver
Hepatocytes	Sinusoidal pattern/basolateral hepatocytes (++) Hepatocyte cytoplasm (+)	(Neg)
Bile duct	Biliary epithelium (++)	(Neg)
Kidney
Glomeruli	Bowman’s capsule (+) Cellular immunostaining common (++)	(Neg) Cellular immunostaining rare to scattered, detected in only 4 of 6 animals (+/++)
Tubules/ducts	Cortex > medulla (+/++)	(Neg)
Pelvis	Urothelium (++)	(Neg)
Skin
Epidermis	(++)	(Neg)
Follicles/adnexa	Follicular epithelium (++) Sebaceous glands (++)	(Neg)
Lung
Airways	Surface epithelium (++)	(Neg)
Alveolar epithelium	Type 2 cells (++) Type 1 cell (+)	(Neg)

(Staining intensity) = Neg negative; + weak; ++ moderate to strong