Table 8.

Results of subgroup analysis for both Asian and Europe/America (West) populations

Virulence factor/region		Clarithromycin			Metronidazole			Amoxicillin			Tetracycline			Levofloxacin
Virulence factor	Region	OR	95% CI	p value	OR	95% CI	p value	OR	95% CI	p value	OR	95% CI	p value	OR	95% CI	p value
cagA	Asia	3.12	0.64–15.17	0.1	5.06	1.24–20.12	0.02	3.26	0.10-97.37	0.49	0.73	0.007–83.60	0.9	5.34	0.04–600.0	0.48
	West	0.87	0.31–2.43	0.7	1.59	0.78–3.21	0.1	19.68	2.74-141.18	0.03	NA	NA	NA	11.33	1.39–91.85	0.02
vacA s1m1	Asia	0.22	0.06–0.81	0.02	0.37	0.15–0.90	0.03	0.08	0.002–2.91	0.16	0.13	0.004–4.76	0.27	0.22	0.01–0.03	0.27
	West	0.65	0.16–2.52	0.5	0.46	0.13–1.58	0.21	16.58	1.77-154.58	0.01	NA	NA	NA	6.25	1.63–23.84	0.01
vacA s1m2	Asia	0.17	0.04–0.71	0.01	0.47	0.14–1.51	0.2	0.11	0.003–3.94	0.22	0.05	0.001–4.66	0.20	0.23	0.01–3.05	0.26
	West	0.10	0.03–0.29	0.01	0.23	0.03–1.41	0.1	NA	NA	NA	NA	NA	NA	0.033	0.006–0.17	0.01
vacA s2m1	Asia	0.04	0.01–0.12	0.07	4.00	0.13-119.23	0.40	0.02	0.01–1.34	0.06	0.02	0.01–1.34	0.06	0.02	0.01–1.34	0.06
	West	0.06	0.01–0.06	0.09	0.01	0.00-0.02	0.5	NA	NA	NA	NA	NA	NA	NA	NA	NA
vacA s2m2	Asia	0.06	0.02–0.19	0.01	0.012	0.006–0.02	0.01	0.044	0.019–0.12	0.01	0.035	0.008–0.14	0.001	0.02	0.007–0.08	0.01
	West	0.07	0.03–0.15	0.01	0.15	0.05–0.42	0.01	0.024	0.003–0.19	0.001	NA	NA	NA	0.12	0.003–5.75	0.28
cagA-vacA s1m1	Asia	0.53	0.38–0.75	0.07	1.31	0.88–1.94	0.17	NA	NA	NA	NA	NA	NA	NA	NA	NA
	West	1.87	0.67–4.86	0.23	0.42	0.07–2.45	0.33	NA	NA	NA	NA	NA	NA	NA	NA	NA

NA not available