Figure 1.

The transcriptional profiles of neutrophils from patients with sepsis differed from those of healthy controls. A: the protocol of isolation of neutrophils from healthy controls (n=3) and patients with sepsis (n=3); B: the top-200 genes with differential expression (fold change greater than two-fold) in neutrophils from patients with sepsis compared with those in healthy controls were selected for heat map analyses; each column depicts one sample; C: enrichment analyses of differentially expressed genes were performed (using the Gene Ontology database) to evaluate enriched biological processes between neutrophils from patients with sepsis and healthy controls; enrichment of regulation of negative regulation of T cell activation-related biological processes was included.