Table 2.
Multivariate Cox regression analysis of PGS in SU2C and Alumkal clinical cohorts.
Cohort | Covariates | Coefficients | SE | P | HR (95% CI) |
---|---|---|---|---|---|
SU2C | Age (<65 vs. ≥65 y/o) | 0.791 | 0.41 | 0.054 | 2.205 (0.987–4.923) |
Gleason score (<7 vs. ≥7) | 0.581 | 0.421 | 0.168 | 1.787 (0.783–4.078) | |
PSA at diagnosis (<20 vs. ≥20 μg/mL) | 0.001 | 0.001 | 0.095 | 1.001 (1.000–1.002) | |
PGS (PGS = 1 vs. PGS = 0) | 1.326 | 0.449 | 0.003 | 3.767 (1.561–9.088) | |
Alumkal | Age (<65 vs. ≥65 y/o) | 0.994 | 0.706 | 0.159 | 2.702 (0.678–10.772) |
Gleason score (<7 vs. ≥7) | 0.339 | 0.522 | 0.516 | 1.404 (0.505–3.905) | |
PSA at diagnosis (<20 vs. ≥20 μg/mL) | 0.557 | 0.596 | 0.350 | 1.746 (0.543–5.613) | |
PGS (PGS = 1 vs. PGS = 0) | 1.741 | 0.61 | 0.004 | 5.702 (1.726–18.842) |