Table 2.

Univariable and multivariable Cox proportional-hazards model regarding RAAS inhibitors withdrawal and all-cause mortality.

Variable	Univariable				Multivariable
	HR	Std. Err.	p value	95% CI	HR	Std. Err.	p value	95% CI
RAASi withdrawal	1.71	0.20	<0.001	1.36-2.15	1.60	0.20	<0.001	1.25-2.04
Age (per year)	1.06	0.01	<0.001	1.05-1.07	1.06	0.01	<0.001	1.04-1.07
Male sex	1.20	0.14	0.118	0.95-1.51	1.33	0.17	0.029	1.03-1.72
Hypertension	0.97	0.23	0.891	0.61-1.54	0.90	0.23	0.681	0.55-1.47
Diabetes Mellitus	1.19	0.14	0.149	0.94-1.49	1.03	0.13	0.800	0.80-1.33
Dyslipidemia	1.34	0.17	0.020	1.05-1.71	1.21	0.16	0.157	0.93-1.58
CHD	1.29	0.19	0.086	0.96-1.73	0.79	0.16	0.262	0.53-1.19
Heart Failure	1.53	0.24	0.007	1.12-2.09	1.11	0.20	0.560	0.78-1.59
TIA/Stroke	1.60	0.25	0.003	1.17-2.18	1.11	0.18	0.518	0.80-1.54
PAD	1.63	0.25	0.001	1.21-2.19	1.42	0.30	0.099	0.94-2.16
CKD	1.61	0.24	0.001	1.20-2.15	0.95	0.15	0.772	0.70-1.31
Hydroxychloroquine	0.56	0.10	0.001	0.40-0.78	0.59	0.12	0.012	0.39-0.89
Lopinavir/Ritonavir	1.10	0.17	0.550	0.81-1.49	0.72	0.14	0.087	0.49-1.05
Azithromycin	0.62	0.07	<0.001	0.49-0.77	0.84	0.11	0.175	0.65-1.08
Corticosteroids	1.72	0.21	<0.001	1.36-2.18	1.84	0.23	<0.001	1.43-2.36

ACEi: angiotensin converting enzyme inhibitors; ARB: angiotensin receptor blockers;; CHD: coronary heart disease; CKD: chronic kidney disease; CRP: C-reactive protein; MRA: mineralocorticoid receptor antagonists; PAD: peripheral artery disease; TIA: transient ischemic attack.