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. 2022 Jun 13;10:874323. doi: 10.3389/fcell.2022.874323

FIGURE 6.

FIGURE 6

Telomerase activity and hTERT mRNA levels in 2 month-old-motor neurons. qPCR analyses of relative levels of telomerase activity in (A) 2 month-old iPSC-derived MNs from 3 control and 3 C9ORF72 carriers, (B) relative levels of telomerase activity in iPSC lines and 2 month-old iPSC-derived MNs from 3 control and 3 C9ORF72 carriers. qPCR analysis of the relative levels of hTERT in (C) 2-month-old iPSC-derived MNs from 3 control subjects or 3 C9ORF72 carriers, (D) relative levels of hTERT in iPSC lines and 2 month-old iPSC-derived MNs from 3 control and 3 C9ORF72 carriers. Two-tailed t-test with Welch’s correction to compare between controls and C9ORF72 MNs and a one-way ANOVA to compare iPSC to iPSC-derived MNs cultures.