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. 2022 Jun 13;10:923769. doi: 10.3389/fcell.2022.923769

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Copyright © 2022 Paolino, Buratta, Mercuri, Pellegrino, Urbanelli, Emiliani, Bertuccini, Iosi, Huber, Brianti, Prezioso, Di Nicola, Federici and Lugini.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Morphological characterization of MV and Exo from plasma of HD and PSO. (A). Scanning electron microscopy analysis of MVHD (a) and ExoHD (b), Bars 500 nm. Transmission electron microscopy analysis of MVHD (c) and ExoHD (e), Bars 200 nm. CD81-Immunoelectron microscopy of MVHD (d) and in ExoHD (f), Bars 100 nm. Scanning electron microscopy analysis of MVPSO (g) and ExoPSO (h), Bars 500 nm. Transmission electron microscopy analysis of MVPSO (i) and ExoPSO (m), Bars 200 nm. CD81-Immunoelectron microscopy of MVPSO (l) and in ExoPSO (n), Bars 100 nm. (B) Nanoparticle tracking analysis (NTA) analysis of MVHD and MVPSO (upper panels) and ExoHD and ExoPSO (lower panels). Representative spectra are shown. Mean, mode, and particles number/ml ([]/ml) are reported in the Table.