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. 2022 Jun 13;9:817517. doi: 10.3389/fmolb.2022.817517

FIGURE 2.

FIGURE 2

Schematic illustration of the regulatory role of lncRNA-encoded micropeptides in muscle physiological processes as well as disease and tumorigenesis and development. (A) Mechanism of action diagram of micropeptide MLN encoded by lncRNA LINC00948 in skeletal muscle physiological process; (B) Mechanism of action diagram of conserved peptide SPAR encoded by lncRNA LINC00961 in muscle regeneration process; (C) Mechanism of action diagram of micropeptide miPEP155 (P155) encoded by lncRNA MIR155HG in immunity and inflammation; (D) Mechanism of action diagram of the 53-aa conserved peptide encoded by lncRNA HOXB-AS3 in CRC; (E) Mechanism of action diagram of the micropeptide SRSP encoded by lncRNA LOC90024 in CRC; (F) Mechanism of action diagram of the micropeptide CASIMO1 encoded by lncRNA NR_029453 in BC; (G) Mechanism of action diagram of the conserved peptide SMIM30 encoded by LINC00998 in HCC; (H) Mechanism of action diagram of the 99-aa conserved peptide KRASIM encoded by lncRNA NCBP2-AS2 interacting with KRAS in HCC; (I) Mechanism of action diagram of the micropeptide PINT87aa encoded by LINC-PINT interacting with FOXM1 in HCC cell senescence; (J) Mechanism of action diagram of the micropeptide RPS4XL encoded by lnc-Rps41 interacting with RPS6 in PASMC.