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miR-146b suppresses inflammation and M1 polarization via inhibiting FGL2 in macrophages. miR-146b mimics and FGL2 overexpression plasmids were co-transfected into LPS-induced macrophages, and the transfection efficacy of FGL2 overexpression was examined by Western blotting (A). The levels of inflammation-related factors were determined by ELISA assay (B), and M1 macrophage polarization-related indicators (C) and the NF-κB and MAPK pathways (D) were determined by Western blotting.
