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. 2022 Jun 13;13:929778. doi: 10.3389/fneur.2022.929778

Table 1.

Summary of reported clinical cases of anti-Homer-3 associated autoimmunity.

References Sex/age (years) Onset Main manifestations MRI findings Treatment Outcome
Zuliani et al. (1) F/65 Subacute CA, vertigo, vomiting Normal Steroids No benefit
Höftberger et al. (6) M/38 Acute CA, encephalitis, seizures, papilledema vomiting Cerebellar atrophy (f-u) Steroids, IVIg Partial recovery
Xu et al. (7) F/51 Insidious CA, dizziness, RBD Cerebellar atrophy (f-u) Hot cross Bun sign Steroids, MMF Partial recovery
Liu et al. (8) F/46 Insidious CA Cerebellar atrophy (f-u) Steroids, MMF Partial recovery
M/14 Subacute CA, encephalitis, myeloradiculopathy Diffuse cerebellar T2W hyperintensities Steroids, IVIg Partial recovery with relapses
M/65 Insidious CA, RBD Cerebellar and pons atrophy (f-u) Hot cross Bun sign Steroids, IVIg, PE No benefit with deterioration
F/84 Subacute CA Normal Steroids Stability
F/69 Subacute CA, encephalopathy, radiculoneuropathy Diffuse cerebral (FLAIR) hyperintensities IVIg, steroids Partial recovery with relapses
This report M/10 Acute CA, encephalopathy Diffuse cerebellar T2W hyperintensities; cerebellar atrophy (f-u) Steroids, IVIg Almost complete recovery

CA, cerebellar ataxia; F-u, follow-up; MMF, mycophenolate mofetil; RBD, REM-sleep behavior disorder.