Figure 6.
Protein–protein interaction (PPI) network of the six aggregation-prone proteins analyzed in this review. Source data was obtained from BioGRID on March 11, 2022, and condensed in Table S1. Here are represented only the proteins that display at least one high-confidence interaction (with number of PPI evidence on BioGRID greater or equal to four), which are depicted with solid lines. Interactions with less than four PPI evidence on BioGRID are represented as dotted lines. The size of the nodes is proportional to the number of interaction(s) with the aggregation-prone proteins, and the nodes are colored as indicated.