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. 2022 Jun 23;15(6):e248869. doi: 10.1136/bcr-2022-248869

Table 2.

Reported cases of Ovarian Carcinoids

Serial number Case report/case series Patients (n) Author (year) Primary/metastatic UL/BL Presence of teratomatous elements in background Evidence of distant metastasis Predominant HPE IHC
1 Case series 35 Robboy et al (1974)19 Metastatic 80% BL 0 92% Not specified Not done
2 Case series 48 Robboy et al (1975)20 Primary 81% UL 76% 0% Insular Not done
3 Case report 1 Finn et al
(1991)21
Metastatic BL Absent Present Insular Neuron-specific enolase, chromogranin, serotonin+
4 Case report 1 Ikeda et al (1991)22 Metastatic BL Absent Present Goblet cell carcinoid Chromogranin A, serotonin+
5 Case series 17 Davis et al (1996)23 Primary 100% UL 63% 35% Insular Not done
6 Case series 329 Soga et al (2000)24 Primary – 57% Insular+trabecular –
7 Case series 17 Strosber et al (2007)25 Metastatic 88% BL Absent 76% Insular Not done
8 Case series 26 Rabban et al (2009)26 16 primary/10
metastatic
100% UL in primary
70% BL in metastatic
62% in primary
Absent in metastatic
6% in primary
60% in metastatic
Insular in both primary and metastatic CDX2+ in
37.2% in primary and 100% in metastatic
9 Case report 1 Chen et al
(2010)27
Primary UL Present Absent Strumal carcinoid Chromogranin, synaptophysin+,
CK7, CK20−
10 Case report 1 Kanayama et al (2012)28 Primary UL Present No Insular Grimelius+, chromogranin A+, synaptophysin+
11 Case report 1 Hinshaw et al
(2012)29
Primary UL Present Absent Strumal carcinoid Synaptophysin, TTF-1
12 Case series 56 Desouki et al (2013)30 46 primary/10 metastatic Details not available 35% in primary
Absent in metastatic
Details not available Insular CDX2+ in 90% metastatic carcinoid, <1

BL, bilateral; IHC, immunohistochemistry; TTF-1, transcription termination factor 1; UL, unilateral.