Table 1. Structure–Activity Relationships of Benzamidazolone Degraders.

^aIndicates n = 2.

^bData represent the geometric mean of at least three replicates. See Tables S1 and S2 for full statistics.

^cMeasured log D determined using the Chrom log D method.

^dKinetic solubility measured by NMR in HEPES buffer at pH 8, containing 4% DMSO.

^eCompound is a racemic mixture of cis isomers.