Table 4.

Residues contributing majorly to the net binding energy of compounds with MELK.

Residue	Compounds
	Top-1	Top-2	Top-3
Ile17	−1.25	−0.67	−0.55
Gly18	−0.80	−1.12	−1.0
Thr19	−0.63	0.34	0.40
Gly20	−1.22	−1.41	−0.84
Val25	−0.83	−0.66	−0.54
Ala38	−1.36	−1.88	−1.00
Lys40	−1.22	−1.28	−1.30
Cys70	−2.41	−2.04	−2.90
Leu86	−0.64	−1.24	−1.67
Glu87	−1.25	−1.63	−2.70
Tyr88	−1.05	−1.35	−2.47
Cys89	−3.67	−2.35	−1.87
Glu136	−4.25	−3.21	−2.55
Asn137	−3.54	−4.01	−5.01
Leu139	−2.31	−1.47	−1.58
Ile149	−1.33	−1.0	−1.21
Asp150	−2.61	−3.67	−6.31