Table 1.
Summary of AaFAS gene family predicted from the Aedes aegypti AaegL5 assembly
| Name | NCBI accession number (AaegL5) | VectorBase accession number (AaegL3) | Max. number of exons | Chro-mo-some | Location | % Ident with human FAS | Length (nucleotides) | Length (amino acids) | No. splice variants/isoforms | Notes on the revised annotation | % identity (AaegL3 and L5) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| AaFAS1 | LOC5568814 | AAEL001194 | 11 | 2 | NC_035108.1 (307544012..307601765, complement) | 45.3 | 9732 | 2422 | 1 | 1 SNP in exon_4 | 99.9 |
| AaFAS2 | LOC5570229 | AAEL008160 | 5 | 3 | NC_035109.1 (9993811..10002427, complement) | 36.7 | 8368 | 2385 | 1 | 1 SNP in exon_5 | 100 |
| AaFAS3 | LOC5573929 | AAEL022506 | 6 | 2 | NC_035108.1 (429256663..429264110, complement) | 32.9 | 7144 | 2334 | 1 | 18 SNPs exon_1, 31 SNPs exon_2, 11 SNPs exon_3, 52 SNPs exon_4, 3 SNPs exon_5, and 12 SNPs exon_6. Deletion of six amino acid residues when compared with the AaegL3 orthologue | 94.6 |
| AaFAS4 | LOC5573931 | AAEL002237 | 6 | 2 | NC_035108.1 (429327062..429334421, complement) | 34.6 | 7068 | 2333 | 1 | 4 SNPs exon_2, 10 SNPs exon_4, 6 SNPs exon_6 | 99.1 |
| AaFAS5 | LOC5573927 | AAEL002228 | 6 | 2 | NC_035108.1 (429228612..429236010, complement) | 32.9 | 7097 | 2324 | 1 | 5 SNPs exon_2, 2 SNPs exon_3, 3 SNPs exon_4, 1 SNP exon_6 | 99.5 |
| AaFAS-like | LOC110675236 | – | 2 | 2 | NC_035108.1 (429280401..429282870, complement) | 36.1 | 2409 | 800 | 1 | – | – |
| AaFAS6 | LOC5573930 | – | 3 | 2 | NC_035108.1 (429275401..429279876, complement) | 36.8 | 4353 | 1386 | 1 | – | – |
The AaegL5 annotation is shown in comparison to the AaegL3 gene models reported by Nene et al. [23]