Table 2.

Results of the pathway analysis using MetaboAnalyst v5.0

Tissue	Pathway	Raw p	Holm adjust	FDR	Impact
Heart	Alanine, aspartate and glutamate metabolism	6.34E−04	5.20E−02	4.05E−02	0.42
	Arginine biosynthesis	3.46E−03	2.80E−01	7.27E−02	0.12
	Phenylalanine, tyrosine and tryptophan biosynthesis	2.63E−02	1.00E+00	2.84E−01	0.5
	d-Glutamine and d-glutamate metabolism	3.92E−02	1.00E+00	3.30E−01	0.5
Liver	Alanine, aspartate and glutamate metabolism	6.61E−03	5.55E−01	5.55E−01	0.22
Kidney	Aminoacyl-tRNA biosynthesis	2.46E−02	1.00E+00	7.37E−01	0.17
Brain	Glycerolipid metabolism	3.15E−02	1.00E+00	9.26E−01	0.24
White adipose	Primary bile acid biosynthesis	5.25E−03	4.41E−01	4.41E−01	0.06

FDR false discovery rate