Table 2.
Basic characteristic of patients, glucose and lipid metabolism parameters among groups of different menstrual cycle length.
<45 days (N = 141) | 45-90 days (N = 264) | >90 days (N = 122) | P value | |
---|---|---|---|---|
Age (y) | 26.33±5.50 | 25.91±5.06 | 25.53±4.47 | 0.437 |
BMI (kg/m2) | 22.76±4.32 | 22.71±3.97 | 22.58±4.38 | 0.946 |
WHR | 0.83±0.07 | 0.82±0.07 | 0.81±0.07 | 0.304 |
LH/FSH | 1.50 ±1.46 c | 1.69±1.00 | 2.01±1.31 a | <0.05 |
T (mmol/L) | 2.05±0.99 | 2.20±1.02 | 2.55±0.98 | <0.05 |
DHEAS (μg/dl) | 2066.37±901.48 | 2112.97±1027.29 | 2263.85±1018.03 | 0.260 |
AFC | 24.90±6.98 c | 25.91±7.93 | 28.03±9.98 a | <0.05 |
FAI | 3.76 (1.98-6.09) | 4.50 (2.68-7.61) | 4.82 (2.84-7.96) | 0.109 |
mFG | 3.00 (2.00-8.00) | 4.00 (2.00-7.00) | 5.00 (2.00-8.00) | 0.198 |
Fasting glucose (mmol/L) | 5.17±0.57 | 5.11±0.52 | 5.04±0.49 | 0.155 |
1h glucose (mmol/L) | 8.17±2.57 | 8.34±2.18 | 8.20±2.32 | 0.727 |
2h glucose (mmol/L) | 6.70±1.91 | 6.80±1.78 | 6.59±1.60 | 0.567 |
Fasting insulin (mU/ml) | 8.06 (4.71-13.11) | 8.06 (5.20-13.90) c | 7.14 (3.81-11.60) b | <0.05 |
1h insulin (mU/ml) | 77.60 (51.50-123.00) b | 82.80 (54.95-136.25)ac | 77.00 (50.40-125.00) b | <0.05 |
2h insulin (mU/ml) | 68.60 (41.70-103.00) | 65.20 (40.75-132.75) | 67.20 (42.20-120.00) | 0.086 |
Delayed insulin peak (%) | 34.75 (49/141) | 35.61 (94/264) | 40.16 (49/122) | 0.601 |
AUCG | 13.65 (11.65-15.85) | 13.48 (11.81-15.79) | 14.30 (12.15-16.25) | 0.744 |
AUGI | 124.35 (78.95-177.74) b | 125.95 (83.83-207.14)ac | 119.29 (76.50-192.57) b | <0.05 |
I/G | 8.63 (6.25-12.62) b | 8.70 (6.21-13.91) a | 8.29 (6.51-13.21) | <0.05 |
HOMA-IR | 1.88 (1.10-3.02) | 1.80 (1.12-2.96) c | 1.59 (0.83-2.66) b | <0.05 |
Adjusted HOMA-IR | 1.83 (1.02-2.97) | 1.96 (1.12-3.-04) c | 1.57 (0.75-2.60) b | <0.05 |
HOMA-β (%) | 103.57 (58.29-168.33) b | 107.89 (61.99-178.45) a | 95.11 (50.53-162.86) | <0.05 |
Adjusted HOMA-β (%) | 117.00 (70.00-170.50) b | 128.00 (82.00-196.00) a | 117.00 (74.00-164.00) | <0.05 |
QUICK I | 0.61 (0.55-0.72) | 0.62 (0.55-0.71) c | 0.64 (0.56-0.79) b | <0.05 |
Adjusted QUICK I | 0.55 (0.49-0.59) | 0.55 (0.49-0.59) | 0.56 (0.51-0.61) | 0.062 |
Matsuda Index | 85.53 (54.59-133.91) b | 80.99 (52.76-136.74)ac | 95.46 (50.39-150.05) b | <0.05 |
Adjusted Matsuda Index | 114.18 (85.05-140.54) | 105.31 (69.46-130.06) | 116.22 (79.67-136.26) | 0.053 |
CHOL (mmol/L) | 4.94±0.88 | 5.05±0.91 | 4.95±1.00 | 0.489 |
TG (mmol/L) | 1.45±1.39 | 1.31±0.72 | 1.39±0.98 | 0.478 |
HDL (mmol/L) | 1.55±0.34 | 1.54±0.38 | 1.57±0.45 | 0.802 |
LDL (mmol/L) | 2.87±0.82 | 3.02±0.84 | 2.87±0.76 | 0.172 |
DHEAS, dehydroepiandrosterone sulfate; AUCG area under the curve of glucose; AUCI, area under the curve of insulin; I/G, the ratio of AUCI and AUCG; Matsuda Index, Matsuda insulin sensitivity index.
P<0.05 when compared with <45 days group.
P<0.05 when compared with 45-90 days group.
P<0.05 when compared with >90 days group.