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Production and properties of Honey Bee venom. A. Prepromelittin sequences from four Apis species show the architecture that is used the production of peptide toxins. A signal sequence directs the protein to secretory pathways and the proprotein stabilizes the peptide until it is released in the venom gland. B. Apis phylogeny inferred form the prepromelittin sequences. C. Relative cytotoxicity of bee and wasp venoms (1).
