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Transient permeabilization of PC bilayers caused by melittin. In vesicle leakage and electrochemical impedance, when P:L is less than 1:200 melittin causes a rapid burst of permeabilization immediately after addition to the bilayers. But almost immediately, leakage dramatically slows with a halftime of 5-10 minutes. In the vesicle studies above, leakage stops before all the contents have been released from the vesicles.
