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. 2022 Jun 27;38(Suppl 1):i350–i358. doi: 10.1093/bioinformatics/btac251

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© The Author(s) 2022. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 5. — Synthetic Case Study 3. DAG labeled as in Figure 3. (a) The signaling model. Nodes are proteins, pointed/flat-headed edges are relationships of typge increase/decrease. (b) Sampling distribution of ${\hat{Q}}_{x} = \hat{E} [Erk | d o (SOS = 70)]$ over 20 observational datasets