. 2022 Mar 31;36(1):2–14. doi: 10.4285/kjt.22.0008

Table 2.

Cambridge criteria of variables associated with successful transplantation of NMP livers [35]

Criteria
• Maximum bile pH >7.5 • Bile glucose concentration <3 mmol/L or >10 mmol/L less than perfusate glucose • Ability to maintain perfusate pH >7.2 without >30 mol bicarbonate supplementation • Falling glucose beyond 2 hours or perfusate glucose under 10 mmol/L, which on challenge with 2.5 g of glucose, does fall subsequently • Peak lactate fall >4.4 mmol/L/kg/hr • Alanine aminotransferase <6,000 U/L at 2 hours

Criteria

• Maximum bile pH >7.5
• Bile glucose concentration <3 mmol/L or >10 mmol/L less than perfusate glucose
• Ability to maintain perfusate pH >7.2 without >30 mol bicarbonate supplementation
• Falling glucose beyond 2 hours or perfusate glucose under 10 mmol/L, which on challenge with 2.5 g of glucose, does fall subsequently
• Peak lactate fall >4.4 mmol/L/kg/hr
• Alanine aminotransferase <6,000 U/L at 2 hours

NMP, normothermic machine perfusion.