TABLE IV.

Structures of HMOS grouped by their core structures.^{28, 32–34, 61}

Core #	Lactose and HMOS	Abbreviations	Symbols	Ref.
I	Lactose (not considered as HMOS itself)	Lac		49
		LNTri II		76
	a2’-Fucosyllactose	2’FL		25
	3-Fucosyllactose	3FL		27
	aLactodifucotetraose	LDFT		77
	3’-Sialyllactose	3’SL		78
	6’-Sulfo-3’-sialyllactose	6’-Sulfo-3’SL		64
	6’-Sialyllactose	6’SL		79
	3’-Sialyl-3-fucosyllactose	3’S3FL		80
II	Lacto-N-tetraose	LNT		24
	aLacto-N-fucopentaose I	LNFP I		26
	bLacto-N-fucopentaose II	LNFP II		81
	Lacto-N-fucopentaose V	LNFP V		82
	a, bLacto-N-difuco-hexaose I	LNDFH I		83
	bLacto-N-difuco-hexaose II	LNDFH II		84
	Sialyllacto-N-tetraose a	LSTa		66
	Sialyllacto-N-tetraose b	LSTb		66
	Disialyllacto-N-tetraose	DSLNT		85
	Sialylfucosyllacto-N-tetraose	S-LNF II or F-LSTa		86
	Fucosylsialyllacto-N-tetraose	S-LNF I or F-LSTb		86
	Fucosyldisialyllacto-N-tetraose	DS-LNF II or FDS-LNT I		87
	Disialylfucosyllacto-N-tetraose	DS-LNF V or FDS-LNT II		87
III	Lacto-N-neotetraose	LNnT		50
	Lacto-N-fucopentaose III	LNFP III		88
	Lacto-N-neofucopentaose V	LNnFP V		89
	Lacto-N-neodifucohexaose II	LNnDFH II (LNDFH III)		67
	Sialyllacto-N-neotetraose c	LSTc		90
	Fucosylsialyllacto-N-neotetroase	F-LSTc		91
IV	Lacto-N-hexaose	LNH		51
	Fucosyllacto-N-hexaose I	FLNH I		92
	Fucosyllacto-N-hexaose II	FLNH II		93
	c4120a			33
	Difucosyllacto-N-hexaose a	DF-LNH a		92
	Difucosyllacto-N-hexaose b	DF-LNH b		51
	Difucosyllacto-N-hexaose c	DF-LNH c		33
	Trifucosyllacto-N-hexaose	TF-LNH		55
	Sialyllacto-N-hexaose	S-LNH		51
	c4021a			34
	Disialyllacto-N-hexaose I	DS-LNH I		94
	Disialyllacto-N-hexaose II	DS-LNH II		94
	Trisialyllacto-N-hexaose	TS-LNH		95
	Fucosylsialyllacto-N-hexaose	FS-LNH		92
	Fucosylsialyllacto-N-hexaose I	FS-LNH I		96
	Fucosylsialyllacto-N-hexaose II	FS-LNH II		96
	Fucosylsialyllacto-N-hexaose III	FS-LNH III		96
	Fucosylsialyllacto-N-hexaose IV	FS-LNH IV		97
	Difucosylsialyllacto-N-hexaose I	DFS-LNH I		96
	Difucosylsialyllacto-N-hexaose II	DFS-LNH II		97
	Fucosyldisialyllacto-N-hexaose I	FDS-LNH I		98
	Fucosyldisialyllacto-N-hexaose II	FDS-LNH II		98
	Fucosyldisialyllacto-N-hexaose III	FDS-LNH III		97
V	Lacto-N-neohexaose	LNnH		52
	Fucosyllacto-N-neohexaose	F-LNnH		52
	Difucosyllacto-N-neohexaose	DF-LNnH		56
	Sialyllacto-N-neohexaose I	S-LNnH I		51
	Sialyllacto-N-neohexaose II	S-LNnH II		80
	Disialyllacto-N-neohexaose	DS-LNnH		87
	Fucosylsialyllacto-N-neohexaose I	FS-LNnH I		80
	Fucosylsialyllacto-N-neohexaose II	FS-LNnH II		52
	Difucosylsialyllacto-N-neohexaose	DFS-LNnH		80
	Fucosyldisialyllacto-N-neohexaose	FDS-LNnH	or	98
VI	para-Lacto-N-hexaose	pLNH		53
	Fucosyl-para-lacto-N-hexaose I	F-pLNH I		99
	Fucosyl-para-lacto-N-hexaose II	F-pLNH II		100
	Fucosyl-para-lacto-N-hexaose IV	F-pLNH IV		100
	Difucosyl-para-lacto-N-hexaose	DF-pLNH		53
	Trifucosyl-para-lacto-N-hexaose I	TF-pLNH I		101
	Trifucosyl-para-lacto-N-hexaose II	TF-pLNH II		100
	Difucosyl-para-lacto-N-hexaose sulfate I	DF-pLNH sulfate I		65
	Difucosyl-para-lacto-N-hexaose sulfate II	DF-pLNH sulfate II		65
	Difucosyl-para-lacto-N-hexaose sulfate III	DF-pLNH sulfate III		65
VII	para-Lacto-N-neohexaose	pLNnH		53
	Fucosyl-para-lacto-N-neohexaose	F-pLNnH or IFLNH III		99
	Difucosyl-para-lacto-N-neohexaose	DF-pLNnH		53
	Trifucosyl-para-lacto-N-neohexaose	TF-pLNnH		100
	c4021b			34
	c4121a			34
	c4121b			34
VIII	Lacto-N-octaose	LNO		54
	c5130c			33
	c5130b			33
	Fucosyllacto-N-octaose	F-LNO		102
	Difucosyllacto-N-octaose I	DF-LNO I		54
	Difucosyllacto-N-octaose II	DF-LNO II		54
	Trifucosyllacto-N-octaose	TF-LNO		54
	c5031a			34
	Fucosylsialyllacto-N-octaose	FS-LNO		103
	c5131a			34
	c5231a			34
	c5231b			34
	Difucosylsialyllacto-N-octaose	DFS-LNO		104
	c5331a			34
IX	Lacto-N-neooctaose	LNnO		54
	Fucosyllacto-N-neooctaose	F-LNnO		54
	Difucosyllacto-N-neooctaose I	DF-LNnO I		54
	Difucosyllacto-N-neooctaose II	DF-LNnO II		54
	Trifucosyllacto-N-neooctaose I	TF-LNnO I		54, 55
	Trifucosyllacto-N-neooctaose II	TF-LNnO II		55
X	iso-Lacto-N-octaose	iLNO		55
	c5130a Fucosyl-iso-Lacto-N-octaose	F-iLNO		33, 105
	Difucosyl-iso-lacto-N-octaose I	DF-iLNO I		106
	Difucosyl-iso-lacto-N-octaose II	DF-iLNO II		106
	c5230a			33
	Trifucosyl-iso-lacto-N-octaose I	TF-iLNO I		55
	Trifucosyl-iso-lacto-N-octaose II	TF-iLNO II		56, 105
	c5330a			33
	Tetrafucosyl-iso-lacto-N-octaose	TetraF-iLNO		56
	pentafucosyl-iso-lacto-N-octaose	PentaF-iLNO		56
	Fucosylsialyl-iso-lacto-N-octaose	FS-iLNO		104
	Difucosylsialyl-iso-lacto-N-octaose I	DFS-iLNO I		104
	Difucosylsialyl-iso-lacto-N-octaose II	DFS-iLNO II		104
	Trifucosylsialyl-iso-lacto-N-octaose	TFS-iLNO		94
XI	para-Lacto-N-octaose	pLNO		56
	Tetrafucosyl-para-lacto-N-octaose	TetraF-pLNO		56
XII	para-Lacto-N-neooctaose	pLNnO		57
XIII	Lacto-N-decaose	LND		58, 107
	Fucosyl-lacto-N-decaose I	F-LND I		107
	Difucosyl-lacto-N-decaose I	DF-LND I		58
	Difucosyl-lacto-N-decaose II	DF-LND II		58
	Difucosyl-lacto-N-decaose III	DF-LND III		58
	Difucosyl-lacto-N-decaose IV	DF-LND IV		58
	Difucosyl-lacto-N-decaose V	DF-LND V		58
	Difucosyl-lacto-N-decaose VI	DF-LND VI		58
				58
				58
	Trifucosyl-lacto-N-decaose I	TriF-LND I		58
	Trifucosyl-lacto-N-decaose II	TriF-LND II		58
	Trifucosyl-lacto-N-decaose III	TriF-LND III		58
	Trifucosyl-lacto-N-decaose IV	TriF-LND IV		58
				58
				58
	c6340a			33
	Tetrafucosyl-lacto-N-decaose I	TetraF-LND I		58
	Tetrafucosyl-lacto-N-decaose II	TetraF-LND II		58
	Tetrafucosyl-lacto-N-decaose III	TetraF-LND III		58
				58
XIV	Lacto-N-neodecaose	LNnD		58
	Fucosyllacto-N-neodecaose I	F-LNnD I		58
	Fucosyllacto-N-neodecaose II	F-LNnD II		58
	Difucosyllacto-N-neodecaose	DF-LNnD		58
	c6041a			34
XV				33
XVI				59
				59
				59
XVII Deviant structures	A antigen-tetrasaccharide	A-Tri		62, 108
	A antigen-pentasaccharide	A-Penta		62, 108–110
	A antigen-hexasaccharide	A-Hexa		62
	A antigen-heptasaccharide	A-Hepta		62, 108, 109
				111
	3’-Sialyl Lewis a	3’SLea		111
	3’-Sialyl-N-acetyllactosamine	3’SLN		34
	6’-Sialyl-N-acetyllactosamine	6’SLN		66
	Fucosylsialyl-novo-lacto-N-pentaose I	FS-novo-LNP I		96
	3’-Galactosyllactose	β3’GL		67
	4’-Galactosyllactose	β4’GL		68
	6’-Galactosyllactose	β6’GL		69

Symbols and abbreviations: N-acetylneuraminic acid (Neu5Ac), fucose (Fuc), galactose (Gal), N-acetylglucosamine (GlcNAc), glucose (Glc), N-acetylgalactosamine (GalNAc).

^aMissing in the milk of Le^a+b− non-secretors.⁷³

^bMissing in the milk of Lewis negative (Le^a−b−) individuals.⁷⁴

^cIndicate the number of Hexose, Fucose, HexNAc, and Neu5Ac in the oligosaccharide.^{33, 34}