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. 2022 Jun 15;110(12):2024–2040.e10. doi: 10.1016/j.neuron.2022.03.032

Figure 8.

Figure 8

Output subtypes of L5 PNs show increased neuronal synchrony

(A) Mice, injected with PHP.eB AAV-CAG-FLEX-GCaMP7s, were imaged in darkness. See Figure S14.

(B and C) Left: schematic neurons and projections patterns (green) (CTX, cortex; STR, striatum; SC, superior colliculus; TH, thalamus). Middle: example activity (grayscale). Right: filled circles: neuronal synchrony of each neuron; solid line: median; shading: distribution; dashed line: awake median. Wilcoxon rank-sum (p < 0.003, prior to Bonferroni correction for 9 comparisons, to include Rbp4-Cre) (bold: significant). See Figure S15. n = neurons in 6 Tlx3-Cre (B), 5 Sim1-Cre (C) mice.