Figure 1.

Piglets with diarrhea showed impaired intestinal morphology and inflammation. a Diarrhea score in weanling piglets. b Water content in the feces of weanling piglets. c Representative colonic morphology of the HE staining results. Arrow, loss of shape in colonic villi. d Representative colonic morphology under the transmission electron microscope. Arrow, unregularly aligned microvilli. Scale bar, 1 μm. e TNF-α level in colonic tissue. f Qualification of F4/80 protein expression. g Qualification of tight junction protein expression. HEA, healthy piglets without diarrhea (n = 11); DIA, diarrheal piglets (n = 13). Data are represented as mean ± SEM. *P < .05, determined by two-tailed Student’s t-test.